Bioactive compounds from Holothuria atra of Indian ocean
نویسندگان
چکیده
The sea cucumber (Holothuria atra) extracts have been evaluated for the presence of bioactive compounds and various biological activities. The methanol extracts showed anti proliferative activities against the Hela and MCF-7 cell lines. Similarly the inhibitory effects of Herpes simplex virus 1 and 2 cells were detected using the plaque reduction assay. The extracts of H. atra were purified using the silica gel column chromatography. The active fractions collected were observed for antimicrobial activity. The GC-MS analysis showed the availability of 59 compounds. The active bioactive compounds found in the H. atra were analyzed and their structure was identified using the (1)HNMR and (13)C NMR experiments.
منابع مشابه
Asexual reproduction parameters and the influence of fission on a <i>Holothuria atra</i> sea cucumber population from a fringing reef on Reunion Island (Indian Ocean)
Holothuria atra is one of the most common sea cucumbers of intertidal zones in the tropical IndianPacific region. Asexual reproduction through transverse fission is a biological phenomenon which has already been studied, most notably in the south of the island of Taiwan (Chao & Chang, 1989; Chao et al., 1994), on the reefs of New Caledonia (Conand, 1989) and on the Great Barrier Reef in Austral...
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